Obesity is a major public health problem, unless there is a satisfactory answer to this problem, the search continues! French researchers followed an original track: they tried to understand how skinny people are to remain.Losing weight through the “gene of thinness”
A rare disease that can help lose weight
Some people suffer from a rare genetic disorder characterized by the absence of a natural enzyme necessary for the digestion process, called the enteropeptidase . The disease prevents the latter to grow regardless of the quantities consumed. The risk is for them to suffer from malnutrition and being perpetually hungry or even starve to death while eating a lot!
French researchers, a start-up biotechnology company ObeTherapy Biotechnology have developed a molecule capable of inhibiting this enzyme, called Obe2008 . Such a molecule could act on the absorption of nutrients and prove an interesting way to combat overweight and diabetes.
To test this molecule, preclinical tests are currently carried out on mice. In a year and a half, human studies may will emerge and a drug could then be available in 7 or 8 years.
The same genes to lose weight and to take
According to the Franco-Swiss team, duplication of a region of chromosome 16 is associated with extreme thinness. If that area is underrepresented, it can play a role in obesity and overweight. Therefore, the identification of genetic variants could be equated with thinness , since the region of chromosome 16 has been identified as having a role in obesity . In fact, 1% of cases of obesity can be explained by a genetic abnormality linked to the disappearance of a fragment of chromosome 16. In short, if certain genes in the same genetic region are present in excess or are too small number, a disease may be triggered, as the sub-weight or obesity.
Lose weight, yes; too thin, no!
Assuming that these searches are successful, it is not obviously will lead to patients with obesity to lose weight without brake. The sub-weight is, like the obesity , a disease with consequences harmful to the health .
The Linecoaching method to stabilize its weight balance . It aims to eat according to its food sensations, what we love, which corresponds in duration to what we need in quantity and quality. Anyway, for those with no genetic abnormality such as those just described above. It addresses the difficulties of order psychological and emotional , leading to eat without hunger , to thwart his painful thoughts and emotions . These key aspects are present in the majority of people are overweight , will be taken into account with you without treatment based on genetics. But no doubt many people would not be opposed to a small boost drug that finally work!